منابع مشابه
Comparison of Memory Impairment and Oxidative Stress Following Single or Repeated Doses Administration of Scopolamine in Rat Hippocampus
Introduction: Scopolamine, a muscarinic cholinergic receptor antagonist, is widely used to induce memory impairment in experimental animals. The present study aims to compare memory impairment and oxidative stress following single and repeated doses administration of scopolamine. Methods: A group of rats received a single shot of scopolamine in different doses (0.5, 1, or 3 mg/kg, IP) 24 hours...
متن کاملRecovery of neuromuscular function after infusion or intermittent bolus doses of atracurium or vecuronium.
Neuromuscular block and postoperative recovery of grip strength and peak expiratory flow (PEF) were compared in patients receiving atracurium or vecuronium administered by continuous infusion or intermittent bolus doses. The same total dose of atracurium (0.92-0.98 mg kg-1) or vecuronium (0.16-0.18 mg kg-1) was given by both methods. A similar degree of neuromuscular block was attained in all g...
متن کاملPharmacokinetics of repeated doses of misoprostol.
BACKGROUND Misoprostol is widely used in obstetrics and gynaecology for medical abortion, cervical priming and induction of labour. To aid the design of effective and safe regimens, we have investigated the pharmacokinetic parameters after the vaginal or sublingual administration of repeated doses of 400 microg of misoprostol. METHODS Women undergoing termination of pregnancy by suction evacu...
متن کاملSedative and ventilatory effects of midazolam infusion: effect of flumazenil reversal.
The purpose of this study was to evaluate the effects of flumazenil (1 mg i.v.) on the ventilatory response of premedicated patients receiving a continuous infusion of midazolam for sedation. After assessing baseline ventilatory function using a modified Read rebreathing method for determining hypercapnic ventilatory drive, 16 healthy outpatients were administered fentanyl, 50 micrograms i.v., ...
متن کاملFlumazenil in the treatment of dizziness and vegetative symptoms after intravenous infusion of paclitaxel.
Accessible online at: www.karger.com/onk Fax +49 761 4 52 07 14 E-mail [email protected] www.karger.com We believe that these symptoms are possibly related to the dehydrogenated ethanol in which the drug is dissolved. Ethanol acts on the central nervous system through multiple mechanisms some of which are not well known. Recent studies [1] have shown that one of these mechanisms is the modu...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1989
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1989.tb11321.x